Lymphocyte blastogenesis to plaque antigens in human periodontal disease.
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چکیده
منابع مشابه
Lymphocyte blastogenesis to plaque antigens in human periodontal disease
Lymphocyte transformation in response to dental plaque antigens has been used to determine the association between cellular immune responses and the periodontal status in man. An in vitro system for lymphocyte transformation was used. Triplicate microcultures of peripheral blood lymphocytes were stimulated with four different concentrations of V. aicalescens, B. melaninogenicus, F. nucleatum, A...
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This study undertook to correlate lymphocyte transformation to human dental plaque antigens with clinical estimates of periodontal disease. Forty-eight patients with periodontal conditions ranging from normal gingivae to severe periodontitis were examined clinically. Oral cleanliness was determined by the Plaque Index System (Sflness & Loe 1964) and gingival health was assessed using the criter...
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The effect of clinical treatment on the in vitro lymphocyte blastogenic response to a panel of dental plaque-associated microorganisms, as well as non-oral antigens, was assessed longitudinally in a group of twenty-three patients during treatment for periodontitis. The patients' blastogenic response to the non-oral antigens remained constant, without significant change, throughout the three yea...
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Lymphocyte blastogenesis and interferon production were measured in adult human leukocyte cultures stimulated with purified or crude cytomegalovirus antigens. Leukocytes from seropositive adults underwent blastogenesis when stimulated with purified or crude Towne strain antigen, whereas neither antigen stimulated blastogenesis in cultures from seronegative donors. The concentrations of antigens...
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Mononuclear leukocytes isloated from the blood of previously treated patients with advanced active Hodgkin disease contained high concentrations of monocytes and showed poor lymphocyte blastogenesis to mitogens. In five of eight patients with disseminated disease, blastogenesis became normal or improved markedly when the leukocyte suspensions were depleted of monocytes before culture. Addition ...
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ژورنال
عنوان ژورنال: Journal of Periodontal Research
سال: 1977
ISSN: 0022-3484,1600-0765
DOI: 10.1111/j.1600-0765.1977.tb00135.x